Synlife

Technology

Technology

 

Synlife is innovating around the synthesis and programming of Synthetic Minimal Cells (Synells).  Synells contain a biochemical mix of proteins  that can transcribe (Tx) and translate (Tl) genes and a DNA program. The Tx/TL mix and DNA is encapsulated in a phospholipid bilayer vesicle called a liposome. Together, these components can reconstitute many of the salient features of living cells. 

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While much of synthetic biology relies on top-down engineering of extant living systems, this strategy is constrained by the fundamental drives of biology, such as evolutionary pressures and resource utilization for replication.

By BUILDING synthetic minimal cells bottom-up, we can reconstitute desirable functions of biology (e.g. sense-and-respond) without incurring many of its drawbacks.


Applications

 

Therapeutics

Programmable drug delivery. 

 
 

Diagnostics

Detection of low abundance molecular markers and cells.

 
 

Screening

High-throughput testing of molecular interactions.